HGNC Database

HGNC: Hugo Gene Nomenclature Committee

The HGNC https://www.genenames.org/, is responsible for approving unique symbols and names for human loci, including protein coding genes, ncRNA genes and pseudogenes, to allow unambiguous scientific communication. For each known human gene it approves a gene name and symbol (short-form abbreviation). All approved symbols are stored in the HGNC database, a curated online repository of HGNC-approved gene nomenclature, gene groups and associated resources including links to genomic, proteomic and phenotypic information. Each symbol is unique and it ensures that each gene is only given one approved gene symbol. It already approved almost 33,000 symbols; the vast majority of these are for protein-coding genes, but also include symbols for pseudogenes, non-coding RNAs, phenotypes and genomic features (see HGNC Search). Individual new symbols are requested by scientists, journals (e.g. Genomics, Nature Genetics) and databases (e.g.Ensembl, Entrez Gene, MGI, RGD and OMIM), and groups of new symbols by those working on gene groups or specific regions of the genome.

TAG Database

TAG:Tumor Associated Genes

Tumor Associated Gene http://www.binfo.ncku.edu.tw/TAG/GeneDoc.php, was designed to utilize information from well-characterized oncogenes and tumor suppressor genes to facilitate cancer research. All target genes were identified through text-mining approach from the PubMed database. A semi-automatic information retrieving engine was built to collect specific information of these target genes from various resources and store in the TAG database. At current stage, 662 TAGs including 246 oncogenes, 265 tumor suppressor genes, and 151 genes related to oncogenesis were collected. Information collected in TAG database can be browsed through user-friendly web interfaces that provide searching genes by chromosome or by keywords. The consensus domain analysis tool functions to identify conserved protein domains and GO terms among selected TAG genes.

TSGENE

TSGENE: Tumor Supressor Gene Database

The database https://bioinfo.uth.edu/TSGene1.0/ allows cancer researchers to search and browse the most comprehensive tumor suppressor gene list with literature evidence. Cancer researchers to access extensive annotations such as cancer mutations, gene expressions from hundreds of tumor and normal samples, computational biologists to download coding and non-coding tumor suppressor genes for further analysis.

ChimerDb

ChimerDB https://www.kobic.re.kr/chimerdb_mirror/is a comprehensive database of fusion genes encompassing analysis of deep sequencing data (ChimerSeq) and text mining of PubMed publications (ChimerPub) with extensive manual annotations (ChimerKB).

DGV

Database of Genomic Variants

The Database of Genomic Variants(DGV) http://dgv.tcag.ca/dgv/app/home is a repository that provides a comprehensive summary of structural variation in the human genome.

CNVD

Copy Number Variation in Disease

CNVD (Copy Number Variation in Disease) https://bioinformaticshome.com/tools/cnv/descriptions/CNVD.htmlis a web-based, manually curated database for copy number variation (CNV) in disease.

DisGeNET Database

DisGeNET: The database integrates information of human gene-disease associations (GDAs) and variant-disease associations (VDAs) from various repositories including Mendelian, complex and environmental diseases.

DisGeNET:https://www.disgenet.org/home/ -